Your brother needs a 4.30+ gear, preferably 4.56's, and he needs to launch above 6500 rpms. Make sure he is shifting at 7000 rpms on every shift!!! I plan on running 150 shot of NOS myself later this year. I don't see 10's being a problem.
Alright, here is the lowdown on my car.
Power:
298 rwhp @ 6300 rpm 294 rwtq @ 4900 rpm
LaRocca's Dynotuned Autologic Chip
24 degrees total timing
13.3 A/F ratio
BBK Longtube Headers, Offroad H, MAC Flowpaths welded into stock pipes, WMS Velocity Tube, Pro-M 87mm MAF, Steeda Pulleys, Steeda Timing Adjuster, the rest of the motor is stock from TB to Oilpan
Driveline:
FRPP Billet Steel Flywheel, McLeod Kevlar Disc, FRPP HD Pressure Plate, Steeda Firewall Adjuster, Tremec T-45, Steeda Tri-Ax Shifter, FRPP Aluminum Driveshaft, FRPP 4.56 gears, TracTech C-Locker, Moser 31 spline Axles, T/A Cover, Axle Tubes Welded
Suspension:
Tokico 5-way Adjustable Drag Struts and Stock Rear Shocks, HPM Megabite Jr. Lower Control Arms and Stock Uppers, FMS "C" springs
Wheels/Tires:
Front - Weld ProStars 15x3.5, Pepboy 165/15 radials, 3.5" ARP wheel studs
Rear - Weld ProStars 15x10, Mickey Thompson ET Drag 26x10 slicks, 3" Moroso wheel studs
Weight Reduction/Removal:
Front Swaybar, Passenger Seat, MLR RearSeat Delete, Spare/Jack, Wipers/Antenna
Race Weight(Guesstimate) = 3290-3300 lbs. with me in the car.
I change the oil, plugs, and fuel filter every 1000-1500 miles. Can you say OVERKILL???
Not bad for a car that dynoed less than 300. After the tune though, it holds the peaks for alot longer than the average N/A Cobra. I don't know if my low dyno numbers are because of the billet steel flywheel or because of driveline friction from having the entire rear built the day of my dynotune. All I know is that the tune does its job at the track, where it counts.
I don't powershift, PERIOD. If I had a trailer, I might try it, but I like being able to drive home after a day at the strip. And I don't consider myself that great of a driver, but I do hit every gear as fast as possible and with authority.

Its not my daily driver anymore, but can easily be driven anywhere.
Lauching at 7600 rpms is awesome to say the least!!! The stock tach looks buried just a hair off of 8000. If anyone desires to launch this high, I suggest a C-Locker, because last month I blew apart a 31 spline Trac-loc in 10 passes.
Sorry for the long post. I hope this answers any questions.
Later, Jason
------------------
N/A 1997 Cobra
1/8 mile -
7.75 @ 88.88 MPH Best MPH - 90.08
1/4 mile -
12.18 @ 113.06 MPH Best MPH - 114.02
1.60 60 ft.