I run Strange 33spl. axles and a spool w/ C-clip elim.'s and the Aerospace rear disc. setup currently... however, last year I had the Baer rear disc setup along with the Strange components and ran them on the street... when I did the Baer install, I had to take the plate the caliper attaches to, to a machine shop to have them milled down to half the thickness where the C-clip elim sat against it (took a gasket with me and they scribed around it and milled it out so the gasket sat down in the plate) ...I had to do this in order to get enough threads to stick out the axle flange in order to start a nut and tighten it down to spec.
I've run a spool on the street, and it's not that bad... just takes some finesse, that's all

Try running that along with a pro-shifted tranny on the street... it's like learning how to drive all over again

...but it can be done!