With a roots blower, its always good to get rid of as much restriction before the supercharger as possible. I'm not sure what the specs on the S281 are, but I would want a 75mm throttle body, 90mm MAF, and a free flowing piping and filter. A X-pipe will defintely help too. 
As far as adding more boost with a pulley, I would upgrade to 38# Cobra or 42# Lightning injectors and that would also be a perfect time for a Ford 90mm MAF. Put the pulley on and get it dyno-tuned with SCT software. You want to make more power, but you want to do it safely as possible. 
		
	
		
		
		
		
		
		
			
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				'97 T-bird LX 4.6L 2V, auto   
SVO heads/intake, Vortech T-trim, front mounted intercooler, blower cams, Cobra crank, Manley H-beam rods, JE pistons, Aeromotive fuel system w/ 42# injectors, and much more 
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