Anytime you have a car out of tune you are going to lose power, but neither of those components should hurt wide open running.
They are ignored during floored open loop cycling.
The TPS may be faulty, which could cause a loss of performance, if it's not reading all the way to wide open, and it's messed up in the low range causing extra gas to be dumped in when it's not needed.
I would also suspect the MAF, and the actual computer in this case too.
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